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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MKI67IP All Species: 10.61
Human Site: Y183 Identified Species: 21.21
UniProt: Q9BYG3 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9BYG3 NP_115766.3 293 34222 Y183 L A K K G I D Y D F P S L I L
Chimpanzee Pan troglodytes XP_515769 261 30438 Y151 L A K K G I D Y D F P S L I L
Rhesus Macaque Macaca mulatta XP_001085690 293 34043 Y183 L A K K G I D Y D F P S L I L
Dog Lupus familis XP_533319 297 34265 S187 G I D Y D F P S L I L H K K E
Cat Felis silvestris
Mouse Mus musculus Q91VE6 317 36247 E206 A V A H R D S E G N Q V L P D
Rat Rattus norvegicus Q5RJM0 271 31333 Y162 L Q M L K M E Y R F K K K E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519520 250 28510 L147 I D Y D F P G L V S K K K V K
Chicken Gallus gallus XP_422088 277 31398 L166 A K M A K R L L R K E N C L R
Frog Xenopus laevis Q7SYS2 278 32306 M157 N K E E V K K M T Q R M I S K
Zebra Danio Brachydanio rerio Q8JIY8 269 30081 K160 H T E D D V K K V G T K L L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002316513 217 25279 A114 P E V A E V V A E C M H N Y L
Maize Zea mays NP_001148652 215 24686 A112 P A V A K V V A D E M N N Y L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88 94.1 73.7 N.A. 56.7 58 N.A. 36.1 50.1 40.6 46 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 88.7 96.9 84.8 N.A. 71.9 73.7 N.A. 50.5 65.1 55.9 61.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 0 N.A. 6.6 20 N.A. 0 0 0 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 0 N.A. 6.6 33.3 N.A. 13.3 13.3 20 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: 27.6 26.6 N.A. N.A. N.A. N.A.
Protein Similarity: 46 43.3 N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 20 N.A. N.A. N.A. N.A.
P-Site Similarity: 20 33.3 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 34 9 25 0 0 0 17 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 0 0 9 0 0 % C
% Asp: 0 9 9 17 17 9 25 0 34 0 0 0 0 0 9 % D
% Glu: 0 9 17 9 9 0 9 9 9 9 9 0 0 9 9 % E
% Phe: 0 0 0 0 9 9 0 0 0 34 0 0 0 0 0 % F
% Gly: 9 0 0 0 25 0 9 0 9 9 0 0 0 0 0 % G
% His: 9 0 0 9 0 0 0 0 0 0 0 17 0 0 0 % H
% Ile: 9 9 0 0 0 25 0 0 0 9 0 0 9 25 0 % I
% Lys: 0 17 25 25 25 9 17 9 0 9 17 25 25 9 25 % K
% Leu: 34 0 0 9 0 0 9 17 9 0 9 0 42 17 42 % L
% Met: 0 0 17 0 0 9 0 9 0 0 17 9 0 0 0 % M
% Asn: 9 0 0 0 0 0 0 0 0 9 0 17 17 0 0 % N
% Pro: 17 0 0 0 0 9 9 0 0 0 25 0 0 9 0 % P
% Gln: 0 9 0 0 0 0 0 0 0 9 9 0 0 0 0 % Q
% Arg: 0 0 0 0 9 9 0 0 17 0 9 0 0 0 9 % R
% Ser: 0 0 0 0 0 0 9 9 0 9 0 25 0 9 9 % S
% Thr: 0 9 0 0 0 0 0 0 9 0 9 0 0 0 0 % T
% Val: 0 9 17 0 9 25 17 0 17 0 0 9 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 9 0 0 0 34 0 0 0 0 0 17 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _